Are you nothing more than glorified “viruses”?

What if I told you your cells’ nuclei may actually be an amalgamation of viral, bacterial, fungal, and other forms of primitive eukaryotic DNA, all working together for the common good:………..YOU!

That’s a pretty humbling thought, isn’t it? Almost on the same level as ashes to ashes and dust to dust. However, we are talking about “living” dust here. Ads on TV talk about the shingles virus already being in you, as if that is the exception rather than the rule. Think about it. Why would the shingles virus find your nuclear DNA to be such an inviting place to take up residence, along with a host of other kinds of viruses? Why indeed. My blog talks about this in quite a bit of detail. You see, I don’t think external viruses entering your body is an exception to anything. They are just “latecomers” in an age old phenomenon that has been going on since life first originated on this planet. Contrary to popular theory, I do not believe the DNA in our chromosomes is merely a long, boring, continuous molecular thread, wound up like a firehose within the nucleus. It is much much more complex than that. There are physical “switches” in the DNA, much like a railroad track, that when triggered force the DNA into different configurations that vary within cell types. These configurations force the DNA to generate RNA and hence protein that is unique to the kind of cell in which they are being generated; in other words, cellular differentiation. When these switches get seriously messed up, the cells do one of two things: they destroy themselves through apoptosis or they become genetically corrupt and capable of evolving over time into something quite sinister: cancer.

Why apoptosis, why cancer? Apoptosis is nature’s way of insuring cancer never happens. It does this by completely destroying the cellular DNA in such as way that none of it “escapes”. Escapes? What does that mean, exactly? Well, such rogue DNA may be capable of taking on a life of its own because of how it was assembled over eons of time. It may even enter normal cells and take up residence in the DNA, just like an external virus, corrupting the genetic machinery of that cell and forcing it to replicate the entire cell in order to replicate the rogue DNA. This is why apoptosis is such a complex and energy intensive process. It must never allow this to happen. The risk to the viability of the organism (in this case, you) is just too great.

You can learn more about how nuclear DNA may have been assembled over the eons by reading through this blog or contacting me.

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About frankabernathy

I am a retired cell biologist and alumnus of Ohio State University. I became interested in chromosomes as far back as the 1960's when I wrote a term paper on the effects of radiomimetic drugs on chromosomes. I was fascinated at how they could break apart and reform new structures so easily. I became further involved in the early 1970's after taking a cytogenetics course at the University of Arkansas. I took that knowledge with me to Ohio State in 1980 where I eventually worked on my research and completed my Ph.D. dissertation, "Studies on Eukaryotic DNA Superstructure". My studies and later research suggested that the DNA within the eukaryotic chromosome is not the simple, linear molecular thread so widely suggested in all the classic textbooks published today. Instead, it may be the culmination of a geologically rapid set of endosymbiotic events where microorganisms plug into each other to create something greater than themselves. Feel free to contact me at fabernathy@sbcglobal.net.
This entry was posted in cellular differentiation, endosymbionts, evolution. Bookmark the permalink.

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