Circular DNA deletions appear widespread in mammals. With further inspection, this may apply throughout the animal kingdom as well and beyond. So what gives? What is this all about? How important is this phenomenon in terms of evolution, cellular differentiation, and cancer? Doesn’t this really depend upon whether these circles are merely curiosities, trivial minor alterations in the genome, or whether they are examples of something much much more? Perhaps they are not the exceptions at all, but rather the reality of how chromosomes are actually put together.
Learn more about these circular structures by reading further into this blog.