Monthly Archives: October 2015

How do you physically build a human being?

Do you want the long or short version? I know, on a blog that’s a pretty silly question. You want the skinniest of the skinny version…right? Ok. I will do my best to comply, using a little dose of entertainment along the … Continue reading

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How can circles within chromosomes be hiding in plain site?

c Above is a mouse L1210 cell as it appears stained with acridine orange under a fluorescent microscope. The green color is due to the high DNA content of the cell which has very little cytoplasm. The cells have been subjected … Continue reading

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Evolution from viruses to man in a nutshell, Part 1

In part one, the hypothetical evolution of the human chromosome from viral beginnings is shown at the DNA level. In later blogs, this will be shown at higher levels of integration. Click on the pics to enlarge them.   

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If chromosomes are masses of DNA circles all stuck together, what does the sticking?

This entire blog has been about throwing out old textbook models of simple linear chromosomes and replacing them with a model of circular DNA’s all stuck together to generate a huge complex mass. This allows the genes to communicate with … Continue reading

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How your chromosomes may actually be put together. Hint: Forget the text books.

Chromosomes are fascinating structures. They are dynamic and highly plastic. They break under conditions of radiation or chemotoxicity, reform into a variety of new structures, and spin off small circular chromosomes called double minutes that get randomly shuffled about in the process of … Continue reading

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Circular DNA crosslinks may be the building blocks that led to your chromosomes

For 50 years, scientists have been well aware of catenated DNA circles (see sample reference link below). Catenated circles can be thought of as links in a metal chain. They are physically interlocked, but otherwise not really connected to one another. Electron microscopy of the circular kinetoplastic … Continue reading

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