When I was growing up we played with something called tinker toys. In fact, they are still available today. There were other baby toys along the way that my children played with called snap lock beads. I’m not here to sell you on toys and how they can be fitted together, but rather on chromosomes and how they may be fitted together. So I am going to show you something that is not yet on the market, at least I am not aware of it.
Imagine, if you will, a can full of three different toy plastic rings that contain short, red magnetic sections like the ones shown below: They come with either one, two, or four magnets attached to them.
These red magnets can be used to attach these three ring types together into any myriad number of configurations, similar to tinker toys and snap beads.
The more rings are networked together, the stronger the bonds become. Single bonds are the weakest links.
Assume these magnets represent origins of replication in DNA circles. There is physical and biochemical strength in numbers. However, even if you pull apart the weak link on the right you still have two single DNA circles, each capable of replication. Further damage would ultimately destroy the rings altogether, but the weakest area of the doublet ring is where the magnets have attached to one another. Please keep this in mind when reading the reference below which states that origins of replication may have something to do with fragile sites in chromosomes. If you need more generalized information, please check out this video link: Human chromosomes made from dust.