The linear DNA model for human chromosomes violates the second law of thermodynamics

DNA circles go into our chromosomes. Conventional theory states that they when they enter, they fuse with the main chromosome and become a linear segment of it. DNA circles also come out of our chromosomes. Conventional theory says this means they have to reform circles prior to exiting the chromosome. The second law of thermodynamics makes the likelihood of regenerating a circle from a fused linear segment more improbable as the size of the DNA circle increases. A quick google search indicates that a broken chromosome from a bacterium like E. coli has a linear length of about 1,200 microns, similar to lengths found in double minute circular chromosomes released from chromosomes like our own when they are damaged by radiation or drugs. Our own cells are in the range of 10 microns in diameter, so a linear chromosome that is 120 times the length of the cell must somehow join together at a single junction point within the cell in the presence of  more than 500 times as much other nuclear DNA to form a circular chromosome. When you really think about it, how can this make any sense? Isn’t it more probable that the circular chromosome pre-existed in the main chromosome and was simple plucked away from an attachment site like a cassette from a tape recorder or a memory chip from a computer?

Read more about this at evolution4.wordpress.com

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About frankabernathy

I am a retired cell biologist and alumnus of Ohio State University. I became interested in chromosomes as far back as the 1960's when I wrote a term paper on the effects of radiomimetic drugs on chromosomes. I was fascinated at how they could break apart and reform new structures so easily. I became further involved in the early 1970's after taking a cytogenetics course at the University of Arkansas. I took that knowledge with me to Ohio State in 1980 where I eventually worked on my research and completed my Ph.D. dissertation, "Studies on Eukaryotic DNA Superstructure". My studies and later research suggested that the DNA within the eukaryotic chromosome is not the simple, linear molecular thread so widely suggested in all the classic textbooks published today. Instead, it may be the culmination of a geologically rapid set of endosymbiotic events where microorganisms plug into each other to create something greater than themselves. Feel free to contact me at fabernathy@sbcglobal.net.
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One Response to The linear DNA model for human chromosomes violates the second law of thermodynamics

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