Can the linear chromosome model be saved?

In my last post (just below this one) I indicated that the linear chromosome model shown in textbooks may violate the second law of thermodynamics because of the sizes of DNA circles that would have to be stitched together from linear fragments to generate double minute chromosomes released by drugs or radiation. A possible exception to this violation may be the known fact that our chromosomes have “loops” of DNA somehow “stitched” together at the linear core of the chromosome. It is possible that the double minutes may have replicated around these loops to generate large circles of DNA without violating the second law of thermodynamics, releasing them into the nucleus as self replicating chromosomes. If so, then, upon destruction of the chromosome, it should merely fall apart into thousands of  linear fragments. After all, loops are not circles, right?

Circles crop

Advertisements

About frankabernathy

I am a retired cell biologist and alumnus of Ohio State University. I became interested in chromosomes as far back as the 1960's when I wrote a term paper on the effects of radiomimetic drugs on chromosomes. I was fascinated at how they could break apart and reform new structures so easily. I became further involved in the early 1970's after taking a cytogenetics course at the University of Arkansas. I took that knowledge with me to Ohio State in 1980 where I eventually worked on my research and completed my Ph.D. dissertation, "Studies on Eukaryotic DNA Superstructure". My studies and later research suggested that the DNA within the eukaryotic chromosome is not the simple, linear molecular thread so widely suggested in all the classic textbooks published today. Instead, it may be the culmination of a geologically rapid set of endosymbiotic events where microorganisms plug into each other to create something greater than themselves. Feel free to contact me at fabernathy@sbcglobal.net.
This entry was posted in Fallacies in science, What are they?. Bookmark the permalink.

19 Responses to Can the linear chromosome model be saved?

  1. Isabell says:

    I am in fact grateful to the owner of this site who has shared this enormous article at at this place.

  2. Very worthwhile information!Ideal! just what I
    was searching for!

  3. Fascinating post, I’m going to spend more hours learning about this subject.

  4. pschyic says:

    I ran across your website last week and began to follow your site content consistently.
    I haven’t left a comment on any sort of blog site just yet but I was considering to start soon. It’s truly exciting
    to actually contribute to an article even if it’s only a blog.
    I really liked reading through a number of your articles.
    Great articles no doubt. I will keep visiting your
    blog frequently. I learned lots from you. Thank you!

  5. This is the kind of information I’ve long been looking for.
    Many thanks for posting this information.

  6. Yes bookmaking this wasn’t a terrible idea. Excellent post!

  7. I had been honored to receive a call from a friend
    as he discovered the key guidelines shared on the website.
    Browsing your article is a true wonderful experience. Many thanks for thinking of readers like me,
    and I wish you the very best.

  8. The good and also insightful articles or blog posts keep me returning here again and again. thank you so much.

  9. Hey there, You have done an admirable job. I’ll certainly digg it and for my
    part recommend to my friends. I’m confident they’ll be benefiting from this excellent website.

  10. I am so thankful for this post and many thanks for
    sharing it with us.

  11. Excellent article, I just passed this to a co-worker who was carrying out a little bit of research on that.
    And he actually ordered me lunch simply because I discovered it for him.

  12. Amazing! This can be one of the most useful blogs i’ve ever arrive across on this subject.
    Actually this is great. I’m also an experienced in this topic
    therefore I can understand your hard work.

  13. Hello there! Excellent articles here. please do keep us updated.

  14. Helpful information. Lucky me I discovered your web site by chance,
    and I am surprised why this coincidence didn’t took place earlier!

    I bookmarked it.

  15. I am genuinely thankful to the owner of this web page who has
    shared this impressive post at at this place.

  16. Remona says:

    Thanks for any other wonderful article. Where else may anybody get that kind of information in such an ideal manner of writing?

    I’ve a presentation subsequent week, and I’m on the look for such information. http://www.uswa.edu.pk/index.php/component/k2/itemlist/user/35294

  17. Sadie says:

    If you desire to obtain a great deal from this post then you have to apply such methods to your won web site. https://en.wikipedia.org/wiki/Gran_Canaria/074/3

  18. Isabel says:

    Awesome website you have here but I was wondering if you knew of any discussion boards that cover the same topics discussed
    here? I’d really love to be a part of community where I can get
    feedback from other experienced people that share the
    same interest. If you have any recommendations, please let me know.
    Bless you! http://itealmendralejo.es/index.php/component/k2/itemlist/user/183838

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s