Genes that boss other genes around

I was nosing around you tube and found a Nova video entitled “What Darwin Never Knew“, July, 2012. What was particularly interesting to me was a section starting around one hour and four minutes into the video. Just prior to this, the video was talking about gene switches that turn other genes off and on. One of the investigators said such genes boss other genes around. This has a striking parallel to the concept of master and slave genes,  models of which are discussed in this blog. In this case, the switches between the master and slave replicons are either left off or permanently turned on by partial fusion of the two adjacent replicons at a shared double origin of replication, generating a promoter region that can now be activated for gene transcription.Fig 17

Fig 18

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About frankabernathy

I am a retired cell biologist and alumnus of Ohio State University. I became interested in chromosomes as far back as the 1960's when I wrote a term paper on the effects of radiomimetic drugs on chromosomes. I was fascinated at how they could break apart and reform new structures so easily. I became further involved in the early 1970's after taking a cytogenetics course at the University of Arkansas. I took that knowledge with me to Ohio State in 1980 where I eventually worked on my research and completed my Ph.D. dissertation, "Studies on Eukaryotic DNA Superstructure". My studies and later research suggested that the DNA within the eukaryotic chromosome is not the simple, linear molecular thread so widely suggested in all the classic textbooks published today. Instead, it may be the culmination of a geologically rapid set of endosymbiotic events where microorganisms plug into each other to create something greater than themselves. Feel free to contact me at fabernathy@sbcglobal.net.
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One Response to Genes that boss other genes around

  1. Loura Shares A Story says:

    Fascinating!

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