Category Archives: cellular differentiation

Ontogeny recapitulates phylogeny

Hiding in Plain Site (III)

In the last two posts I shared photomicrographs of mouse L-1210 cells in various stages of decomposition. The unusual structures generated from nuclei appear to be related to the stage in the cell cycle in which the original cell was … Continue reading

Posted in cancer, cell cycle, cellular differentiation, evolution, What are they? | Leave a comment

Hiding in Plain Site (II)

I assume that the “woosh, over the head” factor was a bit too much in the last post. That’s ok, got to start somewhere, right? Let’s try that one more time. In fact, if I knew how to do it, … Continue reading

Posted in cancer, cell cycle, cellular differentiation, evolution | Leave a comment

The bacteria that gave life to us?

Evidence is piling in that within extreme forms of bacteria called Archaea there is a group called Asgard with DNA fingerprints suggesting ancestry to cells like our own.  It appears that all eukaryotic cells were created by a single endosymbiotic event in … Continue reading

Posted in cellular differentiation, endosymbionts, evolution | Leave a comment

Cancer as a Criminal Entity

What exactly is cancer? I’ve discussed this topic before in a variety of ways but thought it might be useful to bring it up again during the new year. Most everyone knows that cancer is runaway cell growth. At its … Continue reading

Posted in cancer, cellular differentiation, endosymbionts, evolution, Fallacies in science, virus | Leave a comment

Evidence for hierarchical endosymbiosis

In this blog, there are numerous references regarding hierarchical endosymbiosis. Simply put, this phrase means that cells swallowed smaller cells that were, in turn,  swallowed by larger cells and so forth. Not only did this swallowing happen, but the genetic material of … Continue reading

Posted in cellular differentiation, endosymbionts, evolution | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Masters and Slaves

Throughout my scientific career during and after my tenure at Ohio State University, I have promoted the concept of master origins of replication that are associated with tissue differentiation during embryonic development: see Studies on Eukaryotic DNA Superstructure (1988, page 221, pdf … Continue reading

Posted in cellular differentiation, evolution | Leave a comment

If someone is going to fix your car engine, shouldn’t they know how it’s put together?

Why do I keep boring everybody by droning on incessantly about our chromosome structure? Well, if someone is going to fix your car engine, shouldn’t they first know how it’s actually put together? Would you go to a mechanic that starts … Continue reading

Posted in cancer, cellular differentiation, Fallacies in science, What are they? | 38 Comments