Category Archives: cellular differentiation

Ontogeny recapitulates phylogeny

The bacteria that gave life to us?

Evidence is piling in that within extreme forms of bacteria called Archaea there is a group called Asgard with DNA fingerprints suggesting ancestry to cells like our own.  It appears that all eukaryotic cells were created by a single endosymbiotic event in … Continue reading

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Cancer as a Criminal Entity

What exactly is cancer? I’ve discussed this topic before in a variety of ways but thought it might be useful to bring it up again during the new year. Most everyone knows that cancer is runaway cell growth. At its … Continue reading

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Evidence for hierarchical endosymbiosis

In this blog, there are numerous references regarding hierarchical endosymbiosis. Simply put, this phrase means that cells swallowed smaller cells that were, in turn,  swallowed by larger cells and so forth. Not only did this swallowing happen, but the genetic material of … Continue reading

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Masters and Slaves

Throughout my scientific career during and after my tenure at Ohio State University, I have promoted the concept of master origins of replication that are associated with tissue differentiation during embryonic development: see Studies on Eukaryotic DNA Superstructure (1988, page 221, pdf … Continue reading

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If someone is going to fix your car engine, shouldn’t they know how it’s put together?

Why do I keep boring everybody by droning on incessantly about our chromosome structure? Well, if someone is going to fix your car engine, shouldn’t they first know how it’s actually put together? Would you go to a mechanic that starts … Continue reading

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How does a cell become a baby?

Ok, a little bait and switch but not too much. What I am talking about here is something a “wee bit” more abstruse so don’t go all clicky on me and leave. Give me a chance to explain. The cute kittens can wait. It’s tough … Continue reading

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Genes that boss other genes around

I was nosing around you tube and found a Nova video entitled “What Darwin Never Knew“, July, 2012. What was particularly interesting to me was a section starting around one hour and four minutes into the video. Just prior to this, the … Continue reading

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