Aldous Huxley

Aldous Huxley

The facts still stand: How do you generate thousands of circles with orders of magnitude size differences from 40 linear mouse chromosomes? The most obvious answer is that they were already present in a cryptic form (click photos to enlarge).

Circles  91b

Degrading mouse cells, 400x magnification

What do mouse chromosomes look like under “normal” conditions? Check out this link: mouse chromosome.


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Beating DNA into submission

How do you create a simple linear stretch of DNA that goes on and on, like some kind of endlessly meandering oil pipeline?

Well, first of all, you beat the living hell out of it so it breaks up into fragments. Next, get rid of any nonlinear fragments because, face it, they can’t be sequenced anyway. This is most easily done by throwing out the phenol phase used for DNA extraction which may contain any troublesome DNA/protein/lipid etc interactions. Next, take what’s left (linear DNA fragments) and artificially splice them together in your mind using overlapping sequences. If this doesn’t always work, just extrapolate until it does. Voilà! We now have a nice, neat (if somewhat boring) endlessly linear, stretch of DNA.

Circle sequencing

Chromosome Walking2 Chromosome walking 1

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DNA origami, another word for artificial complex DNA superstructure

I find it amazing that scientists are able to tinker with DNA to generate an apparent infinite variety of two and three dimensional objects that are incredibly complex, detailed, and highly symmetrical, some like snowflakes. You can learn more about this nanotechnology by clicking on the link below:

So my question is this: Why is it so difficult to connect the dots here? If man can generate such a wide array of DNA superstructures, why can’t nature? More to the point, the ability to exploit DNA in such a fashion is more than mere coincidence. Nature has been using complex DNA superstructures for eons to generate the chromosomes necessary for the complexity of multicellular life that now exists on this planet.

Natural DNA Origami

Hypothetical natural DNA “origami”           (circa 1991)

Learn more about natural DNA “origami” by reviewing this blog or contacting Dr. Frank Abernathy:

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Another heretical scientist dares to challenge the church of scientific orthodoxy.

This link is very interesting and at first glance seems totally unrelated to what usually appears on my blog. However, though the discovery is quite fascinating and worth reviewing, I mention it here for a different reason: The initial reaction of the scientific community to what they regard as heresy.

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Horizontal gene transfer (still going strong after all these years)

Horizontal gene transfer in this blog suggests that our very chromosomes were constructed by it. Is this a process that happened eons ago and is now relegated to the dustbin of history, occurring only within primitive life forms like bacteria?


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Olympus Bioscapes youtube video link

This video was sent to Bioscapes at their request for their 2014 presentations. It provides technical data on how the substructures shown in this blog were prepared. Additional information can be provided by contacting Dr. Abernathy at ResearchGate or by

Picture legends

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A plant virus that changes the way you think?

Seems a plant virus found in lakes can easily plug into your DNA and change the way you think. Works really well in mice, causing thousands of changes. In order to do this, don’t they need some kind of “plug-in” site?

multi origin replicon evolution  (see models page)

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